Defiance, MO, USA apartments for rent

Ideal for a retreat from city life, this 2-bedroom, 1-bathroom vacation rental is a relaxing getaway! Located in the historic Ruebling House, this apartment fuses antique decor with contemporary furnishings and appliances, including a full kitchen wi...

Charming home is updated with an open floor plan. Backyard has a relaxing gazebo overlooking pond. Pet ducks free range on property. Located on 3 private acres in Defiance area, near award winning Missouri wineries, Katy Trail State Park for hiking a...

A quaint country escape awaits at 'Cabernet Cabin' in Defiance, MO! Ideally suited for couples and families, this 2-bedroom, 1-bath vacation rental home features a cozy interior with a Smart TV, a well-equipped kitchen, and a breezy screened porch. P...

Escape the hustle and bustle of St. Louis with a stay at this chic countryside vacation rental in Defiance, MO. 'Merlot Bungalow' offers a studio interior with a bathroom and a well-equipped kitchenette, perfect for couples and small families seeking...

Free from modern distractions, this 1-bedroom, 1-bath cabin in the heart of wine country is the perfect place to unplug and reconnect with nature! Immersed in lush woodlands, the Defiance vacation rental comes with all the amenities needed for a peac...

Close to Wineries, Hiking & Fishing | Game Room | Fire Pit Raise your glass and let the good times flow at this 3-bed, 2-bath home in Defiance, where you can sip award-winning wines from nearby vineyards, enjoy scenic hikes along the Katy Trail, ...

Experience a unique getaway to the countryside with your family or significant other when you book this modern tiny home in Defiance, MO! With its bright interior and prime location, this 1-bath studio vacation rental is ideal for those seeking chic ...

Avoid the crowds of St. Louis when you escape to Defiance, the ideal spot to access Missouri’s finest wineries. Let the Townview apartment - a 2-bedroom, 2-bathroom vacation rental - be your personal haven. The Ruebling House, built in 1906, was orig...

Brimming with scenic spots, vineyards, and St. Louis thrills, this sleek 1-bedroom + loft, 1-bath cabin offers a true choose-your-own-adventure retreat. Walk to the Katy Trail, kayak in the Missouri River, and explore the Missouri Wine Country. At da...

Guests are sure to enjoy a memorable stay in this fully furnished, 3 bedroom/2 bath ranch home property.  The main/master bedroom has a king-sized bed, while the 2 remaining rooms are furnished with a queen and twin-sized bed (s), comfortable for sle...

Leave the hustle and bustle of city life behind when you escape to The Farmhouse, a 2-bedroom, 1-bathroom vacation rental. Constructed in 1906, The Ruebling House once served as the general store and living quarters of one of Defiance's founding fath...

Adorable, well maintained and updated 1.5 story rental located in the very desirable small town of New Melle, MO and adjacent to Daniel Boone Elementary. Francis Howell Schools. This property is a duplex adjoining a quiet boutique real estate office....

This is a furnished, utilities included, six month, short term lease. Occupancy time frame is from Jan1, 2025thru June30, 2025.Perfect for the corporate contract worker or builders with clients planning on building next winter. Lovely, quality built ...